Nucleolar-based Dux repression is essential for embryonic two-cell stage exit

Upon fertilization, the mammalian embryo must switch from dependence on maternal transcripts to transcribing its own genome, and in mice this involves the transient up-regulation of MERVL transposons and MERVL-driven genes at the two-cell stage. The mechanisms and requirement for MERVL and two-cell...

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Detalles Bibliográficos
Autores principales: Xie, Sheila Q., Leeke, Bryony J., Whilding, Chad, Wagner, Ryan T., Garcia-Llagostera, Ferran, Low, YiXuan, Chammas, Paul, Cheung, Nathan T.-F., Dormann, Dirk, McManus, Michael T., Percharde, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973846/
https://www.ncbi.nlm.nih.gov/pubmed/35273077
http://dx.doi.org/10.1101/gad.349172.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973846/
https://www.ncbi.nlm.nih.gov/pubmed/35273077
http://dx.doi.org/10.1101/gad.349172.121

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