NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation

Cell fate transitions depend on balanced rewiring of transcription and translation programs to mediate ordered developmental progression. Components of the nonsense-mediated mRNA decay (NMD) pathway have been implicated in regulating embryonic stem cell (ESC) differentiation, but the exact mechanism...

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Detalles Bibliográficos
Autores principales: Huth, Michelle, Santini, Laura, Galimberti, Elena, Ramesmayer, Julia, Titz-Teixeira, Fabian, Sehlke, Robert, Oberhuemer, Michael, Stummer, Sarah, Herzog, Veronika, Garmhausen, Marius, Romeike, Merrit, Chugunova, Anastasia, Leesch, Friederike, Holcik, Laurenz, Weipoltshammer, Klara, Lackner, Andreas, Schoefer, Christian, von Haeseler, Arndt, Buecker, Christa, Pauli, Andrea, Ameres, Stefan L., Smith, Austin, Beyer, Andreas, Leeb, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973849/
https://www.ncbi.nlm.nih.gov/pubmed/35241478
http://dx.doi.org/10.1101/gad.347690.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973849/
https://www.ncbi.nlm.nih.gov/pubmed/35241478
http://dx.doi.org/10.1101/gad.347690.120

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