The anti-fibrotic agent nintedanib protects chondrocytes against tumor necrosis factor-ɑ (TNF-ɑ)-induced extracellular matrix degradation

Osteoarthritis is an inflammatory disease of the musculoskeletal system characterized by damaged articular cartilage. Nintedanib is an oral triple kinase inhibitor with anti-fibrotic and anti-inflammatory properties. Thus, we hypothesized that nintedanib might exert a protective effect in chondrocyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chuankun, Qu, Lizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973871/
https://www.ncbi.nlm.nih.gov/pubmed/35164664
http://dx.doi.org/10.1080/21655979.2022.2036899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973871/
https://www.ncbi.nlm.nih.gov/pubmed/35164664
http://dx.doi.org/10.1080/21655979.2022.2036899

Ejemplares similares