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6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway in HeLa cells

This study aimed to elucidate the specific anticancer mechanism of 6-methoxyflavone in HeLa cells. A total of 178 putative targets of 6-methoxyflavone were obtained from the PharmMapper database. Microarray analyses, transcriptome sequencing analyses, functional enrichment analyses, and gene set enr...

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Detalles Bibliográficos
Autores principales: Zhang, Chaihong, Quan, Yuchong, Yang, Lijuan, Bai, Yingying, Yang, Yongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973872/
https://www.ncbi.nlm.nih.gov/pubmed/35246013
http://dx.doi.org/10.1080/21655979.2022.2047496