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Context-dependent DNA polymerization effects can masquerade as DNA modification signals

BACKGROUND: Single molecule measurements of DNA polymerization kinetics provide a sensitive means to detect both secondary structures in DNA and deviations from primary chemical structure as a result of modified bases. In one approach to such analysis, deviations can be inferred by monitoring the be...

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Detalles Bibliográficos
Autores principales: Takahashi, Yusuke, Shoura, Massa, Fire, Andrew, Morishita, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973881/
https://www.ncbi.nlm.nih.gov/pubmed/35361121
http://dx.doi.org/10.1186/s12864-022-08471-2