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Platycodin D regulates high glucose-induced ferroptosis of HK-2 cells through glutathione peroxidase 4 (GPX4)

Diabetic nephropathy (DN) is associated with inflammation. Platycodin D (PD) demonstrates anti-inflammatory activity. However, whether PD affects DN remains to be explored. Here, we aimed to discuss the role of PD in DN and its underlying mechanisms. High glucose (HG)-induced HK-2 cells were treated...

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Detalles Bibliográficos
Autores principales: Huang, Jinzhong, Chen, Gangyi, Wang, Jilei, Liu, Shibin, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973889/
https://www.ncbi.nlm.nih.gov/pubmed/35226829
http://dx.doi.org/10.1080/21655979.2022.2045834