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A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation

BACKGROUND: Systemic lupus erythematosus (SLE), an autoimmune disorder that damages various organ systems, is caused by a combination of genetic and environmental factors. Although germline mutations of several genes are known to cause juvenile SLE, most of the susceptibility genetic variants of adu...

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Detalles Bibliográficos
Autores principales: Law, Sze-Ming, Akizuki, Shuji, Morinobu, Akio, Ohmura, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973904/
https://www.ncbi.nlm.nih.gov/pubmed/35361277
http://dx.doi.org/10.1186/s41232-022-00195-w