Cargando…

Comparison of single copy gene-based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19-directed CAR T cells in treated patients

Chimeric antigen receptor (CAR) T cell therapy with axicabtagene ciloleucel, tisagenlecleucel and brexucabtagen ciloleucel has been adopted as the standard of care for patients with refractory and/or relapsed CD19-positive lymphoid malignancies. Monitoring of kinetics of CAR T cells after administra...

Descripción completa

Detalles Bibliográficos
Autores principales: Schubert, Maria-Luisa, Berger, Carolina, Kunz, Alexander, Schmitt, Anita, Badbaran, Anita, Neuber, Brigitte, Zeschke, Silke, Wang, Lei, Riecken, Kristoffer, Hückelhoven-Krauss, Angela, Müller, Ingo, Müller-Tidow, Carsten, Dreger, Peter, Kröger, Nicolaus, Ayuk, Francis A., Schmitt, Michael, Fehse, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973917/
https://www.ncbi.nlm.nih.gov/pubmed/35294040
http://dx.doi.org/10.3892/ijo.2022.5338