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Comparison of single copy gene-based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19-directed CAR T cells in treated patients

Chimeric antigen receptor (CAR) T cell therapy with axicabtagene ciloleucel, tisagenlecleucel and brexucabtagen ciloleucel has been adopted as the standard of care for patients with refractory and/or relapsed CD19-positive lymphoid malignancies. Monitoring of kinetics of CAR T cells after administra...

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Detalles Bibliográficos
Autores principales:	Schubert, Maria-Luisa, Berger, Carolina, Kunz, Alexander, Schmitt, Anita, Badbaran, Anita, Neuber, Brigitte, Zeschke, Silke, Wang, Lei, Riecken, Kristoffer, Hückelhoven-Krauss, Angela, Müller, Ingo, Müller-Tidow, Carsten, Dreger, Peter, Kröger, Nicolaus, Ayuk, Francis A., Schmitt, Michael, Fehse, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973917/ https://www.ncbi.nlm.nih.gov/pubmed/35294040 http://dx.doi.org/10.3892/ijo.2022.5338

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