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MicroRNA-326 impairs chemotherapy resistance in non small cell lung cancer by suppressing histone deacetylase SIRT1-mediated HIF1α and elevating VEGFA

Compelling evidence has implicated the role of microRNAs (miRs or miRNAs) in lung cancer. Sirtuin-1 (SIRT1) is a key contributor to the progression of non-small cell lung cancer (NSCLC). This study was intended to investigate whether miR-326 affected NSCLC associated with SIRT1. miR-326 and SIRT1 ex...

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Detalles Bibliográficos
Autores principales: Wei, Jinying, Meng, Guangping, Wu, Jing, Wang, Ying, Zhang, Qiang, Dong, Ting, Bao, Jin, Wang, Chunyan, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973918/
https://www.ncbi.nlm.nih.gov/pubmed/34696659
http://dx.doi.org/10.1080/21655979.2021.1993718