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Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer

Shikonin (SHK), a major component of shiverweed, was provided with anti-tumor effects via multiple targets and signal pathways. Nevertheless, the specific mechanism of its function in colorectal cancer (CRC) still needed to be further explored. The study was designed to examine the role of SHK in CR...

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Detalles Bibliográficos
Autores principales: Hu, ZhiWei, Zhou, XinDong, Zeng, DeQiang, Lai, JiaJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973937/
https://www.ncbi.nlm.nih.gov/pubmed/35192430
http://dx.doi.org/10.1080/21655979.2021.2024638