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Impact of CYLD on chromatin structure and histone methylation in malignant melanoma

The tumor suppressive role of CYLD lysine 63 deubiquitinase (CYLD) is known in melanoma. To the best of our knowledge, however, the precise mechanism underlying the tumor suppressive function of CYLD has yet to be clarified. In the present study, a novel melanoma mouse model was generated, which rev...

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Detalles Bibliográficos
Autores principales: Schott, Mandy, Kappelmann-Fenzl, Melanie, Fischer, Stefan, Fernandez-Barrena, Maite G., Pineda-Lucena, Antonio, Ávila, Matías A., Kuphal, Silke, Bosserhoff, Anja-Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973957/
https://www.ncbi.nlm.nih.gov/pubmed/35293595
http://dx.doi.org/10.3892/ijmm.2022.5122