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LncRNA miR-17-92a-1 cluster host gene (MIR17HG) promotes neuronal damage and microglial activation by targeting the microRNA-153-3p/alpha-synuclein axis in Parkinson’s disease

Long noncoding RNAs (lncRNAs) have been regarded as modulators of neurodegenerative diseases. Here, we addressed the role of lncRNA miR-17-92a-1 cluster host gene (MIR17HG) in Parkinson’s disease (PD). C57BL/6 mice and SH-SY5Y cells were intervened with 6-hydroxydopamine (6-OHDA) to set up PD models...

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Detalles Bibliográficos
Autores principales: Zhang, Jianzhong, Yang, Yun, Zhou, Chaoyang, Zhu, Ronglan, Xiao, Xiang, Zhou, Bin, Wan, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974023/
https://www.ncbi.nlm.nih.gov/pubmed/35137671
http://dx.doi.org/10.1080/21655979.2022.2033409