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Albumin-binding tag derived Exendin-4 analogue for treating hyperglycemia and diabetic complications

Current study was conducted to design and screen a long-lasting Exendin-4 analog for treating type 2 diabetes via the novel strategy of albumin binding combined with thrombin enzymolysis. First, a series of fusion peptides, containing different albumin-binding tags, a determinate thrombin-cleavable...

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Detalles Bibliográficos
Autores principales: Xu, Shujuan, Wang, Fang, Li, Hui, Wang, Ya, Fang, Dongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974032/
https://www.ncbi.nlm.nih.gov/pubmed/34696658
http://dx.doi.org/10.1080/21655979.2021.1995993