Zebularine protects against blood-brain-barrier (BBB) disruption through increasing the expression of zona occludens-1 (ZO-1) and vascular endothelial (VE)-cadherin

Blood-brain-barrier (BBB) disruption is an important pathological characteristic of ischemic stroke (IS) and mainly results from dysfunction of brain vascular endothelial cells and tight junctions. Zebularine is a novel inhibitor of DNA methyltransferase (DNMT). Here, we assessed its effects on BBB...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangliang, He, Guohua, Yang, Xirong, Xu, Guoyao, Tang, Yidan, Li, Hanwen, Yu, Bing, Wang, Zhen, Xu, Wei, Song, Kangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974047/
https://www.ncbi.nlm.nih.gov/pubmed/35112992
http://dx.doi.org/10.1080/21655979.2021.2024323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974047/
https://www.ncbi.nlm.nih.gov/pubmed/35112992
http://dx.doi.org/10.1080/21655979.2021.2024323

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