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Increased FUN14 domain containing 1 (FUNDC1) ubiquitination level inhibits mitophagy and alleviates the injury in hypoxia-induced trophoblast cells

Preeclampsia (PE) is a pregnancy disorder characterized by excessive trophoblast cell death. This study aims to explore the exact mechanism of the ubiquitination level of FUN14 domain containing 1 (FUNDC1) in mitophagy and injury in hypoxic trophoblast cells. In this study, HTR-8/SVneo trophoblast c...

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Detalles Bibliográficos
Autores principales: Chen, GuoQing, Chen, Lu, Huang, Yan, Zhu, XiongShan, Yu, YuanLan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974051/
https://www.ncbi.nlm.nih.gov/pubmed/34699308
http://dx.doi.org/10.1080/21655979.2021.1997132