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Circular RNA circHIPK3 is downregulated in diabetic cardiomyopathy and overexpression of circHIPK3 suppresses PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis

It has been reported that circHIPK3 can be downregulated by high glucose, suggesting its potential involvement in diabetes and diabetic complications. This study aimed to explore the role of circHIPK3 in diabetic cardiomyopathy (DC). PTEN is a kind of tumor suppressor gene, which is very commonly lo...

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Detalles Bibliográficos
Autores principales: Jiang, Jun, Gao, Guannan, Pan, Qiang, Liu, Jing, Tian, Yu, Zhang, Xiaoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974065/
https://www.ncbi.nlm.nih.gov/pubmed/35200097
http://dx.doi.org/10.1080/21655979.2022.2031395