Fumitremorgin C alleviates advanced glycation end products (AGE)-induced chondrocyte inflammation and collagen II and aggrecan degradation through sirtuin-1 (SIRT1)/nuclear factor (NF)-κB/ mitogen-activated protein kinase (MAPK)

Fumitremorgin C is a potent and selective inhibitor of the breast cancer resistance protein. This study aimed to explore the role of fumitremorgin C in osteoarthritis (OA) and disclose the underlying mechanism. The cell viability of AGE-treated SW1353 cells in the presence of fumitremorgin C was det...

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Detalles Bibliográficos
Autores principales: Zhou, Yeli, Li, Jing, Wang, Chenglong, Pan, Zheer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974073/
https://www.ncbi.nlm.nih.gov/pubmed/35109750
http://dx.doi.org/10.1080/21655979.2021.2024387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974073/
https://www.ncbi.nlm.nih.gov/pubmed/35109750
http://dx.doi.org/10.1080/21655979.2021.2024387

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