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miR-129-5p restores cardiac function in rats with chronic heart failure by targeting the E3 ubiquitin ligase Smurf1 and promoting PTEN expression

Chronic heart failure (CHF) is a prevalent health concern with complex pathogenesis. This current study set out to estimate the function of the miR-129-5p/Smurf1/PTEN axis on cardiac function injury in CHF. The model of CHF in rats was established. The cardiac function indexes, myocardial tissue dam...

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Detalles Bibliográficos
Autores principales: Qi, Yuan, Tang, Yan, Yin, Lu, Ding, Keke, Zhao, Cuimei, Yan, Wenwen, Yao, Yi’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974089/
https://www.ncbi.nlm.nih.gov/pubmed/35034538
http://dx.doi.org/10.1080/21655979.2021.2024335