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miR-129-5p restores cardiac function in rats with chronic heart failure by targeting the E3 ubiquitin ligase Smurf1 and promoting PTEN expression
Chronic heart failure (CHF) is a prevalent health concern with complex pathogenesis. This current study set out to estimate the function of the miR-129-5p/Smurf1/PTEN axis on cardiac function injury in CHF. The model of CHF in rats was established. The cardiac function indexes, myocardial tissue dam...
Autores principales: | Qi, Yuan, Tang, Yan, Yin, Lu, Ding, Keke, Zhao, Cuimei, Yan, Wenwen, Yao, Yi’an |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974089/ https://www.ncbi.nlm.nih.gov/pubmed/35034538 http://dx.doi.org/10.1080/21655979.2021.2024335 |
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