DEPTH2: an mRNA-based algorithm to evaluate intratumor heterogeneity without reference to normal controls

BACKGROUND: Intratumor heterogeneity (ITH) is associated with tumor progression, unfavorable prognosis, immunosuppression, genomic instability, and therapeutic resistance. Thus, evaluation of ITH levels is valuable in cancer diagnosis and treatment. METHODS: We proposed a new mRNA-based ITH evaluati...

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Detalles Bibliográficos
Autores principales: Song, Dandan, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974098/
https://www.ncbi.nlm.nih.gov/pubmed/35365157
http://dx.doi.org/10.1186/s12967-022-03355-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974098/
https://www.ncbi.nlm.nih.gov/pubmed/35365157
http://dx.doi.org/10.1186/s12967-022-03355-1

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