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Small activating RNA activation of ATOH1 promotes regeneration of human inner ear hair cells

The loss of inner ear hair cells leads to irreversible acoustic injury in mammals, and regeneration of inner ear hair cells to restore hearing loss is challenging. ATOH1 is a key gene in the development and regeneration of hair cells. Small activating RNAs (saRNAs) can target a gene to specifically...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Li, Kang, Moorim, Wu, Jian-Cheng, Xie, Meng-Yao, Xue, Ruo-Yan, Tang, Qi, Yang, Hua, Li, Long-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974106/
https://www.ncbi.nlm.nih.gov/pubmed/35246011
http://dx.doi.org/10.1080/21655979.2022.2045835