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Downregulation of cathepsin C alleviates endothelial cell dysfunction by suppressing p38 MAPK/NF-κB pathway in preeclampsia

Endothelial cell dysfunction is an essential pathophysiological feature of preeclampsia (PE). It has been reported that cathepsin C is upregulated in the maternal vascular endothelium of PE patients. The excessive activation of p38 MAPK leads to various diseases, including PE. NF-κB pathway can prom...

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Detalles Bibliográficos
Autores principales: Lu, Fan, Gong, Han, Lei, Houkang, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974117/
https://www.ncbi.nlm.nih.gov/pubmed/35037834
http://dx.doi.org/10.1080/21655979.2021.2023994