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Cilengitide, an αvβ3-integrin inhibitor, enhances the efficacy of anti-programmed cell death-1 therapy in a murine melanoma model

Integrins play an important role in multiple stages of tumor progression and metastasis. Previous studies have shown synergistic effects of combined αvβ6-integrin and αvβ8-integrin inhibitors with immunotherapy. However, the role of αvβ3-integrin inhibitor in tumor immunity is still unclear. In this...

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Detalles Bibliográficos
Autores principales: Pan, Xin, Yi, Minxiao, Liu, Chaofan, Jin, Yu, Liu, Bo, Hu, Guangyuan, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974133/
https://www.ncbi.nlm.nih.gov/pubmed/35142593
http://dx.doi.org/10.1080/21655979.2022.2029236