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Tetrandrine reduces oxidative stress, apoptosis, and extracellular matrix degradation and improves intervertebral disc degeneration by inducing autophagy

Tetrandrine (TET) was reported to be an autophagy agonist, and the activating autophagy could delay intervertebral disc degeneration (IDD). Our study focused on exploring whether TET attenuated tert butyl hydrogen peroxide (TBHP)-induced nucleus pulposus (NP) cell injury and delayed rat IDD by induc...

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Detalles Bibliográficos
Autores principales: Liu, Jintao, Yu, Pengfei, Dai, Feng, Jiang, Hong, Ma, Zhijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974165/
https://www.ncbi.nlm.nih.gov/pubmed/35109761
http://dx.doi.org/10.1080/21655979.2022.2031396