Cargando…

Forkhead box protein 1 transcriptionally activates sestrin1 to alleviate oxidized low-density lipoprotein-induced inflammation and lipid accumulation in macrophages

Transcription factor forkhead box protein 1 (FOXP1) has been shown cardiovascular protection. We aimed to analyze the role of FOXP1 in oxidized low-density lipoprotein (ox-LDL)-induced macrophages and its possible regulatory effect on sestrin1 (SESN1) expression. After stimulation with ox-LDL, FOXP1...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Feng, Zhao, Yongcheng, Zhang, Bin, Xiao, Chunwei, Sun, Zhanfa, Gao, Yuan, Dou, Xueyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974195/
https://www.ncbi.nlm.nih.gov/pubmed/35043753
http://dx.doi.org/10.1080/21655979.2021.2000228