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Cortical atrophy and amyloid and tau deposition in Down syndrome: A longitudinal study

Introduction: The Down syndrome population has a high prevalence for dementia, often showing their first clinical symptoms in their 40s. Methods: In a longitudinal cohort, we investigate whether amyloid deposition at time point 1 (TP1) could predict cortical thickness change at time point 2 (TP2). T...

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Detalles Bibliográficos
Autores principales: Padilla, Concepcion, Montal, Victor, Walpert, Madeleine J., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Hartley, Sigan L., Cohen, Ann D., Tudorascu, Dana L, Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Holland, Anthony J., Zaman, Shahid H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974205/
https://www.ncbi.nlm.nih.gov/pubmed/35386472
http://dx.doi.org/10.1002/dad2.12288