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SET domain containing 7 promotes oxygen-glucose deprivation/reoxygenation-induced PC12 cell inflammation and oxidative stress by regulating Keap1/Nrf2/ARE and NF-κB pathways

Oxidative stress and inflammation are implicated in the pathogenesis of cerebral ischemia-reperfusion (I/R) injury. SETD7 (SET Domain Containing 7) functions as a histone lysine methyltransferase, participates in cardiac lineage commitment, and silence of SETD7 exerts anti-inflammatory or antioxidan...

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Detalles Bibliográficos
Autores principales: Pan, Xianfang, Fan, Jin, Peng, Fang, Xiao, Li, Yang, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974222/
https://www.ncbi.nlm.nih.gov/pubmed/35259059
http://dx.doi.org/10.1080/21655979.2022.2045830