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The endosomal pH regulator NHE9 is a driver of stemness in glioblastoma

A small population of self-renewing stem cells initiate tumors and maintain therapeutic resistance in glioblastoma (GBM). Given the limited treatment options and dismal prognosis for this disease, there is urgent need to identify drivers of stem cells that could be druggable targets. Previous work s...

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Detalles Bibliográficos
Autores principales: Ko, Myungjun, Makena, Monish R, Schiapparelli, Paula, Suarez-Meade, Paola, Mekile, Allatah X, Lal, Bachchu, Lopez-Bertoni, Hernando, Kozielski, Kristen L, Green, Jordan J, Laterra, John, Quiñones-Hinojosa, Alfredo, Rao, Rajini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974362/
https://www.ncbi.nlm.nih.gov/pubmed/35387234
http://dx.doi.org/10.1093/pnasnexus/pgac013