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Elevated IL-35 level and iTr35 subset increase the bacterial burden and lung lesions in Mycobacterium tuberculosis-infected mice

This study aimed to investigate the relationship between interleukin (IL)-35 level and IL-35-producing regulatory T cells (iTr35 subset) in Mycobacterium tuberculosis (Mtb)-infected mice. After the mice were injected with Mtb strain H37R via tail vein, the bacterial burden, lung lesions, and the imp...

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Detalles Bibliográficos
Autores principales: Yu, Fangliu, Zhu, Xinying, Li, Qingdeng, Xu, Wenqin, Gao, Yunxing, Wen, Yufeng, Zhang, Qiong, Dou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974395/
https://www.ncbi.nlm.nih.gov/pubmed/35434368
http://dx.doi.org/10.1515/biol-2022-0025