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Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue

Clear-cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma (RCC), and its progression has been linked to chronic inflammation. About 70% of the ccRCC cases are associated with inactivation of the von Hippel–Lindau (VHL) tumor-suppressor gene. However, it is still n...

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Detalles Bibliográficos
Autores principales: Nguyen-Tran, Hieu-Huy, Nguyen, Thi-Ngoc, Chen, Chen-Yun, Hsu, Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974431/
https://www.ncbi.nlm.nih.gov/pubmed/34301760
http://dx.doi.org/10.1158/0008-5472.CAN-21-0345