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Translational Analysis of Moderate to Severe Asthma GWAS Signals Into Candidate Causal Genes and Their Functional, Tissue-Dependent and Disease-Related Associations
Asthma affects more than 300 million people globally and is both under diagnosed and under treated. The most recent and largest genome-wide association study investigating moderate to severe asthma to date was carried out in 2019 and identified 25 independent signals. However, as new and in-depth do...
Autores principales: | Portelli, Michael A., Rakkar, Kamini, Hu, Sile, Guo, Yike, Adcock, Ian M., Sayers, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974692/ https://www.ncbi.nlm.nih.gov/pubmed/35386986 http://dx.doi.org/10.3389/falgy.2021.738741 |
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