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Antigen Uptake After Intradermal Microinjection Depends on Antigen Nature and Formulation, but Not on Injection Depth

The skin is an attractive alternative administration route for allergy vaccination, as the skin is rich in dendritic cells (DCs) and is easily accessible. In the skin multiple subsets of DCs with distinct roles reside at different depths. In this study antigen (=allergen for allergy) formulations we...

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Detalles Bibliográficos
Autores principales: Leboux, Romain J. T., Schipper, Pim, van Capel, Toni M. M., Kong, Lily, van der Maaden, Koen, Kros, Alexander, Jiskoot, Wim, de Jong, Esther C., Bouwstra, Joke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974696/
https://www.ncbi.nlm.nih.gov/pubmed/35386985
http://dx.doi.org/10.3389/falgy.2021.642788