Risk Assessment in Drug Hypersensitivity: Detecting Small Molecules Which Outsmart the Immune System

Drug hypersensitivity (DH) reactions are clinically unusual because the underlying immune stimulations are not antigen-driven, but due to non-covalent drug-protein binding. The drugs may bind to immune receptors like HLA or TCR which elicits a strong T cell reaction (p-i concept), the binding may en...

Descripción completa

Detalles Bibliográficos
Autores principales: Pichler, Werner J., Watkins, Stephen, Yerly, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Allergy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974731/
https://www.ncbi.nlm.nih.gov/pubmed/35386664
http://dx.doi.org/10.3389/falgy.2022.827893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974731/
https://www.ncbi.nlm.nih.gov/pubmed/35386664
http://dx.doi.org/10.3389/falgy.2022.827893

Ejemplares similares