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Risk Assessment in Drug Hypersensitivity: Detecting Small Molecules Which Outsmart the Immune System
Drug hypersensitivity (DH) reactions are clinically unusual because the underlying immune stimulations are not antigen-driven, but due to non-covalent drug-protein binding. The drugs may bind to immune receptors like HLA or TCR which elicits a strong T cell reaction (p-i concept), the binding may en...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974731/ https://www.ncbi.nlm.nih.gov/pubmed/35386664 http://dx.doi.org/10.3389/falgy.2022.827893 |