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Regular Use of Depot Medroxyprogesterone Acetate Causes Thinning of the Superficial Lining and Apical Distribution of Human Immunodeficiency Virus Target Cells in the Human Ectocervix

BACKGROUND: The hormonal contraceptive depot medroxyprogesterone acetate (DMPA) may be associated with an increased risk of acquiring human immunodeficiency virus (HIV). We hypothesize that DMPA use influences the ectocervical tissue architecture and HIV target cell localization. METHODS: Quantitati...

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Detalles Bibliográficos
Autores principales: Edfeldt, Gabriella, Lajoie, Julie, Röhl, Maria, Oyugi, Julius, Åhlberg, Alexandra, Khalilzadeh-Binicy, Behnaz, Bradley, Frideborg, Mack, Matthias, Kimani, Joshua, Omollo, Kenneth, Wählby, Carolina, Fowke, Keith R, Broliden, Kristina, Tjernlund, Annelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974825/
https://www.ncbi.nlm.nih.gov/pubmed/32780807
http://dx.doi.org/10.1093/infdis/jiaa514