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Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time

Human immunodeficiency virus (HIV) persists in cells despite antiretroviral therapy; however, the influence of cellular mechanisms such as activation, differentiation, and proliferation upon the distribution of proviruses over time is unclear. To address this, we used full-length sequencing to exami...

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Detalles Bibliográficos
Autores principales: Horsburgh, Bethany A, Hiener, Bonnie, Fisher, Katie, Lee, Eunok, Morgan, Hannah, Eden, John-Sebastian, von Stockenstrom, Susanne, Odevall, Lina, Milush, Jeffrey M, Hoh, Rebecca, Fromentin, Rémi, Chomont, Nicolas, Hecht, Frederick M, Schlub, Timothy E, Deeks, Steven G, Palmer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974828/
https://www.ncbi.nlm.nih.gov/pubmed/34037766
http://dx.doi.org/10.1093/infdis/jiab291