Cargando…
Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time
Human immunodeficiency virus (HIV) persists in cells despite antiretroviral therapy; however, the influence of cellular mechanisms such as activation, differentiation, and proliferation upon the distribution of proviruses over time is unclear. To address this, we used full-length sequencing to exami...
Autores principales: | Horsburgh, Bethany A, Hiener, Bonnie, Fisher, Katie, Lee, Eunok, Morgan, Hannah, Eden, John-Sebastian, von Stockenstrom, Susanne, Odevall, Lina, Milush, Jeffrey M, Hoh, Rebecca, Fromentin, Rémi, Chomont, Nicolas, Hecht, Frederick M, Schlub, Timothy E, Deeks, Steven G, Palmer, Sarah |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974828/ https://www.ncbi.nlm.nih.gov/pubmed/34037766 http://dx.doi.org/10.1093/infdis/jiab291 |
Ejemplares similares
-
Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
por: Hiener, Bonnie, et al.
Publicado: (2018) -
Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites
por: Lee, Eunok, et al.
Publicado: (2020) -
Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4
por: Fisher, Katie, et al.
Publicado: (2023) -
Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy
por: Lee, Eunok, et al.
Publicado: (2019) -
The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4(+) T cells
por: Duette, Gabriel, et al.
Publicado: (2022)