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Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-κB Response

Clostridioides difficile infection (CDI) represents a significant burden on the health care system, one that is exacerbated by the emergence of binary toxin (CDT)-producing hypervirulent C. difficile strains. Previous work from our laboratory has shown that Toll-like receptor 2 (TLR2) recognizes CDT...

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Detalles Bibliográficos
Autores principales: Simpson, Morgan, Frisbee, Alyse, Kumar, Pankaj, Schwan, Carsten, Aktories, Klaus, Petri, William A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974845/
https://www.ncbi.nlm.nih.gov/pubmed/33011801
http://dx.doi.org/10.1093/infdis/jiaa620