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Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-κB Response
Clostridioides difficile infection (CDI) represents a significant burden on the health care system, one that is exacerbated by the emergence of binary toxin (CDT)-producing hypervirulent C. difficile strains. Previous work from our laboratory has shown that Toll-like receptor 2 (TLR2) recognizes CDT...
Autores principales: | Simpson, Morgan, Frisbee, Alyse, Kumar, Pankaj, Schwan, Carsten, Aktories, Klaus, Petri, William A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974845/ https://www.ncbi.nlm.nih.gov/pubmed/33011801 http://dx.doi.org/10.1093/infdis/jiaa620 |
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