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Dynamic regulation of GATA2 in fate determination in hematopoiesis: possible approach to hPSC-derived hematopoietic stem/progenitor cells

GATA2, a principal member of the GATA family, plays important roles in the generation and maintenance of hematopoietic stem/progenitor cells. Among the three mRNA transcripts, the distal first exon of GATA2 (IS exon) is specific for hematopoietic and neuronal cells. GATA2 mutants with abnormal expre...

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Detalles Bibliográficos
Autores principales: Zhou, Ya, Mao, Bin, Chen, Yijin, Xue, Yuan, Chen, Bo, Zhang, Yonggang, Ma, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974898/
https://www.ncbi.nlm.nih.gov/pubmed/35399862
http://dx.doi.org/10.1097/BS9.0000000000000040