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Therapeutic Drug Monitoring of Anti-Thymocyte Globulin in Allogeneic Stem Cell Transplantation: Proof of Concept

Anti-thymocyte globulin (ATG), a polyclonal antibody, is used in allogeneic hematopoietic cell transplantation (HCT) to prevent graft-vs.-host-disease (GvHD) and graft failure (GF). Overexposure to ATG leads to poor early T-cell recovery, which is associated with viral infections and poor survival....

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Detalles Bibliográficos
Autores principales: Meesters-Ensing, J.I., Admiraal, R., Ebskamp, L., Lacna, A., Boelens, J. J., Lindemans, C. A., Nierkens, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974913/
https://www.ncbi.nlm.nih.gov/pubmed/35370695
http://dx.doi.org/10.3389/fphar.2022.828094