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Therapeutic Drug Monitoring of Anti-Thymocyte Globulin in Allogeneic Stem Cell Transplantation: Proof of Concept
Anti-thymocyte globulin (ATG), a polyclonal antibody, is used in allogeneic hematopoietic cell transplantation (HCT) to prevent graft-vs.-host-disease (GvHD) and graft failure (GF). Overexposure to ATG leads to poor early T-cell recovery, which is associated with viral infections and poor survival....
Autores principales: | Meesters-Ensing, J.I., Admiraal, R., Ebskamp, L., Lacna, A., Boelens, J. J., Lindemans, C. A., Nierkens, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974913/ https://www.ncbi.nlm.nih.gov/pubmed/35370695 http://dx.doi.org/10.3389/fphar.2022.828094 |
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