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RNA editing enzyme ADAR1 is required for early T cell development

The RNA editing enzyme ADAR1 has been shown to be an essential molecule for hematopoietic cell differentiation, embryonic development, and regulation of immune responses. Here, we present evidence in a T-cell-specific gene knockout mouse model that ADAR1 is required for early T cell development. Los...

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Detalles Bibliográficos
Autores principales: Xufeng, Richard, Nie, Daibang, Yang, Qiong, Wang, Wang, Cheng, Tao, Wang, Qingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974940/
https://www.ncbi.nlm.nih.gov/pubmed/35399867
http://dx.doi.org/10.1097/BS9.0000000000000039