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Two-step protocol for regeneration of immunocompetent T cells from mouse pluripotent stem cells

Numerous efforts have been attempted to regenerate T cells in culture dish from pluripotent stem cells (PSCs). However, in vitro generated T cells exhibited extremely low activity and compromised immunocompetency in vivo. Here, we describe a two-step protocol for regenerating functional T cells usin...

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Detalles Bibliográficos
Autores principales: Wang, Tongjie, Lv, Cui, Hu, Fangxiao, Liu, Lijuan, Wang, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974948/
https://www.ncbi.nlm.nih.gov/pubmed/35402823
http://dx.doi.org/10.1097/BS9.0000000000000049