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Loss of Tet2 affects platelet function but not coagulation in mice

Ten-eleven translocation 2 (TET2) functions as a methylcytosine dioxygenase that catalyzes the iterative oxidation of 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. TET2 has been shown to be crucial for the maintenance and differentiation of hematopoietic stem...

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Detalles Bibliográficos
Autores principales: Wang, Bichen, Xia, Meijuan, Chen, Ting, Li, Mengke, Shi, Deyang, Wang, Xiaomin, Pang, Aiming, Zhou, Jiaxi, Yuan, Weiping, Chu, Yajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974955/
https://www.ncbi.nlm.nih.gov/pubmed/35400021
http://dx.doi.org/10.1097/BS9.0000000000000055