ALKBH3 is dispensable in maintaining hematopoietic stem cells but forced ALKBH3 rectified the differentiation skewing of aged hematopoietic stem cells

ALKBH3, a demethylase responsible for demethylating N1-methyladenosine (m(1)A) in mRNA and N1-methyldeoxyadenosine in single-stranded DNA, plays an important role in DNA repair and cancer cell proliferation. However, its function in hematopoietic stem cells (HSCs) is unknown. In this study, we gener...

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Detalles Bibliográficos
Autores principales: He, Hanqing, Wang, Yuqian, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975010/
https://www.ncbi.nlm.nih.gov/pubmed/35400026
http://dx.doi.org/10.1097/BS9.0000000000000057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975010/
https://www.ncbi.nlm.nih.gov/pubmed/35400026
http://dx.doi.org/10.1097/BS9.0000000000000057

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