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A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model
Neutrophils are essential immune cells that defend the host against pathogenic microbial agents. Neutrophils are produced in the bone marrow and are retained there through CXCR4–CXCL12 signaling. However, patients with the Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975054/ https://www.ncbi.nlm.nih.gov/pubmed/35402788 http://dx.doi.org/10.1097/BS9.0000000000000019 |