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A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model

Neutrophils are essential immune cells that defend the host against pathogenic microbial agents. Neutrophils are produced in the bone marrow and are retained there through CXCR4–CXCL12 signaling. However, patients with the Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome a...

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Detalles Bibliográficos
Autores principales: Yip, Ai Kia, Balachander, Akhila, Tan, Leonard D.L., Liong, Ka Hang, Tan, Rui Zhen, Balabanian, Karl, Bachelerie, Francoise, Ng, Lai Guan, Chiam, Keng-Hwee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975054/
https://www.ncbi.nlm.nih.gov/pubmed/35402788
http://dx.doi.org/10.1097/BS9.0000000000000019