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Molecular mechanisms for stemness maintenance of acute myeloid leukemia stem cells

Human acute myeloid leukemia (AML) is a fatal hematologic malignancy characterized with accumulation of myeloid blasts and differentiation arrest. The development of AML is associated with a serial of genetic and epigenetic alterations mainly occurred in hematopoietic stem and progenitor cells (HSPC...

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Detalles Bibliográficos
Autores principales: Wang, Jiazhen, Wang, Peipei, Zhang, Tiantian, Gao, Zhuying, Wang, Jing, Feng, Mengdie, Yin, Rong, Zhang, Haojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975089/
https://www.ncbi.nlm.nih.gov/pubmed/35402786
http://dx.doi.org/10.1097/BS9.0000000000000020