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Tumor heterogeneity of acute myeloid leukemia: insights from single-cell sequencing
Individual tumors comprise genetically and epigenetically heterogeneous subclones, each of which is presumably associated with a distinct function, such as self-renewal or drug sensitivity. The dissection of such intratumoral heterogeneity is crucial to understand how tumors evolve during disease pr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975104/ https://www.ncbi.nlm.nih.gov/pubmed/35402804 http://dx.doi.org/10.1097/BS9.0000000000000015 |