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Tumor heterogeneity of acute myeloid leukemia: insights from single-cell sequencing

Individual tumors comprise genetically and epigenetically heterogeneous subclones, each of which is presumably associated with a distinct function, such as self-renewal or drug sensitivity. The dissection of such intratumoral heterogeneity is crucial to understand how tumors evolve during disease pr...

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Detalles Bibliográficos
Autores principales: Chen, AiLi, Hu, ShaoYan, Wang, Qian-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975104/
https://www.ncbi.nlm.nih.gov/pubmed/35402804
http://dx.doi.org/10.1097/BS9.0000000000000015